Brain  Tumors  and
Other Diseases of the Central Nervous System
Cases  Correlating  Neuroimaging and  Neuropathology
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Updated  27/12/15 e-mails : gradanat@fcm.unicamp.br___gradanat@unicamp.br
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Added in 2003 e 2004
2005, 2006
2007, 2008 2009, 2010 2011, 2012 2013, 2014 2015, 2016
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General and Special Pathology  Neuropathology and Neuroimaging Neuroimaging Basics Neuroimaging - Cases
Alphabetical index (Pathology) Alphabetical index (Neuro) Neuro Image Bank Neuropathology - Cases
English Homepage This page in Portuguese Site in Portuguese New additions
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Cases  posted  in  2009 and 2010
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28/12/10
M. 1 yr.  Desmoplastic infantile astrocytoma M. 29 yr.  Germinoma of pineal
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M. 21 yr. Germinoma of  hypothalamic region infiltrating dorsum sellae, cavernous sinuses and compressing optic chiasm  F. 16 yr. Germinoma of  hypothalamic region disseminating to IV ventricle
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F. 20 yr. Pineoblastoma F. 14 yr. Pineoblastoma
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F. 24 yr. Pineocytoma F. 58 yr. Three-lobed cyst of pineal
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7/11/10
M. 49 yr.  Gliosarcoma of left frontal lobe M. 29 yr. Left parietal primitive neuroectodermal tumor (PNET)
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F. 5 months. Glioblastoma multiforme of left cerebral hemisphere (presumably congenital) F. 49 yr. Pseudotumoral demyelinating lesions in right cerebral hemisphere
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6/9/10
M. 15 yr.  Occipital paraventricular pleomorphic xanthoastrocytoma. Recurrence after  five years  F. 27 yr. Giant cell glioblastoma
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M. 3 months. Choroid plexus carcinoma F. 27 yr. Intradiploic arachnoid cyst
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M. 45 yr. Cervical epidural meningeal cyst  F. 15 yr. Multiple epidural meningeal cysts
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7/7/10
M. 22 yr.  Ganglioglioma of cerebellum F. 13 yr.  Severe multiple sclerosis in early adolescence.  Two-year follow up
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M. 25 yr.  Hypothalamic hamartoma  F. 3 yr. Hypothalamic hamartoma
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M. 49 yr. Giant invasive pituitary adenoma infiltrating skull base and nasopharynx  F. 37 yr. Anaplastic primitive neuroectodermal tumor  (PNET) of left frontal lobe. 
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23/5/10
M. 17 yr. Primary myxoid sarcoma of brain. Three recurrences over four years M. 4 d.  Congenital PNET (primitive neuroectodermal tumor) of cerebral hemisphere with ependymal and neuroblastic differentiation. 
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F. 15 yr. pPNET (peripheral primitive neuroectodermal tumor) / Ewing's sarcoma of spinal epidural space  at T11-T12 level F. 26 yr. Myxopapillary ependymoma 
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9/4/10
F. 75 yr. Metastatic adenocarcinoma in sphenoid wing mimicking meningioma on MRI M. 59 yr. Metastatic neuroendocrine carcinoma in cerebral hemisphere
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F. 25 yr. Extradural capillary hemangioma of ligamentum flavum compressing thoracic spinal cord F. 37 yr.  Rathke's cleft cyst
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18/2/10
M. 33 yr. Hemangiopericytoma with falx attachment M. 4 d. Congenital gliosarcoma at foramen of Monro
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F. 57 yr. Capillary telangiectases  associated with cortical dysplasia  M. 46 yr.  Esthesioneuroblastoma causing frontal lobe hemorrhage
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30/12/09
F. 68 yr. Skull metastasis of follicular adenocarcinoma of thyroid F. 49 yr. Subependymoma of lateral ventricle 
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F. 54 yr. Paraganglioma of cauda equina M. 47 yr. Frontal arteriovenous malformation (AVM)
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9/12/09
F. 36 yr. Choroid plexus papilloma of fourth ventricle F. 1 yr 7 m. Choroid plexus carcinoma of lateral ventricle with  seeding through CSF pathways
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M. 28 yr. Multiple schwannomas of cauda equina. Predominance of Antoni B pattern M. 26 yr. Peripheral primitive neuroectodermal tumor (pPNET) of cauda equina
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3/11/09
M. 24 yr. Occipital pilocytic astrocytoma featuring grossly abnormal vessels, leptomeningeal and parenchymal infiltration and ventricular seeding. M. 63 yr. Cerebellar pilocytic astrocytoma with atypia and high Ki-67 index.
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M. 38 yr. Left parietal cavernoma (cavernous hemangioma) extending from ventricle to hemispheric surface. F. 75 yr. Fibroblastic meningioma of left lateral ventricle. 
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M. 25 yr. Dermoid cyst (mature cystic teratoma) of sellar region. Spread of lipid droplets through subarachnoid space and lateral ventricle. M. 33 yr.  Epidermoid cyst of right choroid fissure and arachnoid cyst of posterior fossa.
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27/7/09
M. 4 yr.  Tanycytic ependymoma of third ventricle and foramina of Monro M. 6 yr. Right sided parieto-occipital tanycytic ependymoma 
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F. 28 yr.  Large occipital cavernoma (cavernous hemangioma) M. 24 yr. Spinal enterogenous cyst 
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F. 59 yr.  Left sided temporal glioblastoma multiforme  Same case 9 months after surgery and radiotherapy - pseudotumoral radiation necrosis  of left frontal lobe
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16/6/09
F. 32 yr. Solid-cystic ganglioglioma 
with pilocytic glial component in cerebellum
M. 62 yr. Anaplastic pilocytic astrocytoma of right frontal lobe
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F. 56 yr. Marginal zone non Hodgkin B cell lymphoma of skull base at left cavernous sinus  F. 45 yr.  Plasmacytoma of skull base
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19/5/09
M. 44 yr. Adamantinomatous craniopharyngioma  extending into third ventricle M. 54 yr.   Adamantinomatous craniopharyngioma.  Large cyst filling prepontine cistern and  third ventricle
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M. 44 yr. Adamantinomatous craniopharyngioma extending into frontal lobes  M. 31 yr. Neuroimaging highly suggestive of craniopharyngioma - third ventricle cyst with fluid level. On histology - pilocytic gliosis, cholesterol granulomas, but no tumor tissue. 
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28/2/09
F. 29 yr.  Complex meningioma combining rhabdoid, papillary  and clear cell patterns F. 66 yr. Parafalcine meningioma with microcystic, xanthomatous, angiomatous and meningothelial  components
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M. 49 yr.  Xanthomatous and angiomatous meningioma of left parietal convexity M. 56 yr. Left temporal gliosarcoma
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7/1/09
F. 40 yr. Frontoethmoidal (frontonasal) cephalocele F. 5 yr.  Frontoethmoidal (fronto-orbital) cephalocele 
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M.  51 yr. Lipidized meningioma of sphenoid wing  F. 42 yr. Recurrent chordoid meningioma invading frontal sinus
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F. 37 yr. Ewing's sarcoma / primitive neuroectodermal tumor (PNET) of lumbar nerve roots invading vertebrae M. 21 yr. Primitive neuroectodermal tumor (PNET) of lumbar nerve roots with paravertebral soft tissue extension
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Added in 2003 e 2004
2005, 2006
2007, 2008 2009, 2010 2011, 2012 2013, 2014 2015, 2016
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Cases  posted  in  2007 and 2008
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30/11/08
M. 43 yr.  Right  parietal astroblastoma F. 43 yr.  Chordoid glioma of third ventricle 
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M. 42 yr.  Chondroma of skull base at petrous apex / cavernous sinus F. 60 yr. Primary dural lymphoma with extracranial extension. 12-year follow-up
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F. 48 yr.  Pseudotumoral demyelinating lesion of   cerebral hemispheric white matter F. 67 yr. Necrotic cysticercus cellulosae of cerebral hemisphere - reactional changes in brain tissue 
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2/10/08

F. 15 yr. Bilobed, solid and cystic pilocytic astrocytoma of cerebellum with abundant vascular proliferation  F. 29 yr.  Solid-cystic right parietal ganglioglioma with  features of xanthoastrocytoma
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M. 27 yr. Schwannoma of trigeminal nerve root or of Gasserian ganglion F. 27 yr. Diffusely infiltrating, non contrast enhancing B cell lymphoma
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M. 60 yr.  Widespread cerebral metastases of lung adenocarcinoma  M. 22 yr.  Two metastases of choriocarcinoma (primary in mediastinum)
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31/7/08

Subependymoma of lateral ventricle Frontal ependymoblastoma
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Pilocytic astrocytoma of midbrain tegmentum and pons with cerebellar extension Pilocytic astrocytoma of midbrain. Leptomeningeal infiltration and desmoplastic reaction.
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Cystic frontal pilocytic astrocytoma 
with abundant vascular proliferation 
Pilocytic astrocytoma of chiasmatic region and third ventricle
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6/1/08
Fronto-parietal anaplastic oligoastrocytoma treated by surgery, radio- and chemotherapy  Same case, late pseudotumoral radiation necrosis after 5 years 
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Meningioma of optic nerve sheath  Clear cell meningioma of posterior fossa
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Olfactory neuroblastoma Retroperitonial neuroblastoma  metastatic to skull
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Recurrent ependymoma of foramen of Luschka with hyaline core rosettes Cellular ependymoma of posterior horn of lateral ventricle. Dot pattern reactivity to EMA 
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Diffuse low grade frontal astrocytoma with incipient anaplasia Frontal oligoastrocytoma 
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27/7/07
Heavily calcified left frontal oligodendroglioma with abundant minigemistocytes. 7-year follow up and anaplastic transformation Basal oligodendroglioma of right hemisphere with abundant minigemistocytes
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Papillary craniopharyngioma with squamous epithelium Papillary craniopharyngioma with cubic epithelium
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30/5/07
Systemic T/NK cell lymphoma involving brain and spinal cord, masquerading as multiple sclerosis Occipital bone metastasis of follicular adenocarcinoma of thyroid. Four-year history
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Secretory meningioma of sphenoid wing with hyperostosis and extension into middle fossa and orbit. F. 6 yr.  Gliomatosis cerebri (rapidly growing, extensively infiltrative anaplastic astrocytoma).
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Non-Taylor cortical dysplasia with small pleomorphic xanthoastrocytoma (chance finding) Solid-cystic temporal xanthoastrocytoma with cytoplasmic glycogen deposits
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F. 11 yr.  Diffuse thalamic astrocytoma with anaplastic foci. High positivity for Ki-67 and p53 Central Neurocytoma 
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23/2/07
Aggressive pilocytic astrocytoma of vermis infiltrating meninges. Exuberant vascular proliferation  Cystic and infiltrative pilocytic astrocytoma of vermis in the 8th decade
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Pilocytic astrocytoma of vermis with ventricular seeding Pilocytic astrocytoma of optic chiasm and third ventricle. Dual histological pattern: pilocytic and diffuse with gemistocytic astrocytes
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Pilocytic astrocytoma of basal cerebral hemisphere with marked nuclear atypia and explosive growth in four months Pilocytic astrocytoma of basal cerebral hemisphere with high cellularity and recurrence in four months
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Pilocytic astrocytoma of spinal cord Pilocytic astrocytoma of frontal pole with exuberant vascular proliferation 
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4/1/07
Echinococcosis of the central nervous system.  Ganglioglioma with  sarcomatous component.
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Pseudotumoral multiple sclerosis. Central pontine myelinolysis
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Non Langerhans histiocytosis  of skull base and sellar region. Non Langerhans histiocytosis  of meninges and brain. 
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Langerhans histiocytosis (eosinophil granuloma) of skull and sternum Osteosarcoma of clivus secondary to irradiation for craniopharyngioma
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Updated  27/12/15 e-mails : gradanat@fcm.unicamp.br___gradanat@unicamp.br
...
Added in 2003 e 2004
2005, 2006
2007, 2008 2009, 2010 2011, 2012 2013, 2014 2015, 2016
..
General and Special Pathology  Neuropathology and Neuroimaging Neuroimaging Basics Neuroimaging - Cases
Alphabetical index (Pathology) Alphabetical index (Neuro) Neuro Image Bank Neuropathology - Cases
English Homepage This page in Portuguese Site in Portuguese New additions
.....