Brain  Tumors  and
Other Diseases of the Central Nervous System
Cases  Correlating  Neuroimaging and  Neuropathology
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Updated 5/1/2020 e-mails : gradanat@yahoo.com.br___gradanat@unicamp.br 
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Additions  2003 - 2006
2007 - 2010
2011 - 2014 2015 -  2018 2019 to present
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General and Special Pathology  Neuropathology and Neuroimaging Neuroimaging Basics Neuroimaging - Cases
Alphabetical index (Pathology) Alphabetical index (Neuro) Neuro Image Bank Neuropathology - Cases
English Homepage This page in Portuguese Histological techniques New additions
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Cases  posted  in  2011 to 2014
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30/12/14
M. 55 yr.   Occipital epidural solitary fibrous tumor penetrating through bone M. 52 yr.   Occipital / cervical intra- and extracranial solitary fibrous tumor. 10 year follow up and late metastases to thoracic vertebrae
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M. 47 yr.  Temporal arterio-venous malformation. F. 42 yr.   Intraventricular Cysticercus cellulosae.
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F. 60 yr.  Glioblastoma multiforme of midbrain and pineal region F. 31 yr. Chondroma of skull base 
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29/10/14
F. 1 yr 8 m.  Herpes simplex encephalitis, acute phase M. 47 yr. 
Paracoccidioidomycosis. Multiple nodular cerebral lesions with peripheral contrast enhancement mimicking metastases 
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F. 10 yr.  Choroid plexus carcinoma F. 67 yr. Hemangiopericytoma of sellar region mimicking pituitary adenoma
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M. 14 yr. Germinoma of hypothalamic region and III ventricle F. 54 yr. Metastatic  melanoma in head of caudate nucleus, with peritumoral and intraventricular hemorrhage 
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22/8/14
F. 36 yr.  Primitive neuroectodermal tumor (PNET) of brainstem at IV ventricle floor M. 8 yr. Pilomyxoid astrocytoma at septum pellucidum 
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F. 51 yr.  Sarcoidosis of falx and dura mater of cerebral convexity M. 38 yr. Small temporal chordoid meningioma
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M. 56 yr.  Granular cell tumor of neurohypophysis at III ventricle floor M. 43 yr. Leukodystrophy with spongiform changes of white matter reminiscent of Canavan's disease
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22/4/14
M. 19 yr.  Primary sarcoma of cerebral cortex  F. 38 yr.  Peripheral primitive neuroectodermal tumor (pPNET) of sacral plexus and sciatic nerve
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M. 20 yr.  Aneurysmal bone cyst of skull and spontaneous (non traumatic) epidural hematoma F. 52 yr.  Central neurocytoma incarcerating the choroid plexus
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31/12/13
F. 72 yr. Creutzfeldt-Jakob disease (spongiform encephalopathy) M. 38 yr.  Circumscribed tuberculous meningitis in HIV + patient
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M. 36 yr.  Granular cell tumor of neurohypophysis M. 52 yr.  Hemangioblastoma of medulla oblongata
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F. 32 yr.  Chordoma of clivus F. 1 yr. 6 m.  Intraspinal dermoid cyst
F. 44 yr. Intraspinal psammomatous meningioma  F. 30 yr. Microcystic meningioma of greater sphenoid wing, causing hyperostosis
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30/10/13
M. 4 m.  Occipital encephalocele M. 16 yr.  Cystic, partially ossified chondroma of brain convexity with dural attachment
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F. 27 yr.  Pseudotumoral toxoplasmosis in right parietal lobe F. 77 yr.  Clear cell ependymoma of cervical spinal cord
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27/9/13
M. 34 yr.  Cryptococcoma of right parietal lobe M. 5 mths.  Choroid plexus cyst of left lateral ventricle
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F. 14 yr.   Pilocytic astrocytoma of quadrigeminal plate with CSF seeding of lumbosacral cul-de-sac F. 5 yr.   Pilomyxoid astrocytoma
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13/7/13
M. 19 yr.  Chondromyxoid fibroma  of occipital bone; intra-  and extracranial extension M.  6 m. Choroid plexus papilloma of lateral ventricle
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M. 29 yr.  Anaplastic astrocytoma  of lumbar spinal cord M. 52 yr. Pineocytoma
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31/5/13
F. 48 yr.  Right temporal gliosarcoma F. 48 yr.  Chordoid meningioma of olfactory groove invading nasal cavity
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F. 48 yr.  Single demyelinating lesion of right parieto-occipital region F. 62 yr.  Amyloid angiopathy and brain hemorrhage
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26/2/13
M. 27 yr.  Occipital aneurysmal bone cyst F. 17 yr.  Skull base chondroblastoma (temporal bone) 
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F. 64 yr.  Glioblastoma multiforme of pineal F. 56 yr.  Psammomatous meningioma of olfactory groove
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F. 52 yr.  B cell lymphoma of dura mater, occipital bone and soft tissues M. 61 yr. Skull base plasmacytoma (occipital and temporal bones) 
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Cases  posted  in  2011 and 2012
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20/12/12
F. 20 yr.  Dysembryoplastic neuroepithelial tumor (DNT) of right superior frontal gyrus.  M. 13 yr. DNT of left pre-central gyrus 
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F. 68 yr.  Exophytic meningioma of lesser sphenoid wing with hyperostotic nodule at implantation M. 64 yr. Dermoid cyst  (mature teratoma) in cerebellar vermis + posterior fossa arachnoid cyst
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5/12/12
F. 64 yr.  Bifrontal desmoplastic ganglioglioma  above the corpus callosum with areas of central neurocytoma M. 30 yr. Hemangiopericytoma of tentorium cerebelli
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18/9/12
F. 43 yr.  Supratentorial primitive neuroectodermal tumor (PNET). M. 25 yr.  Ganglioglioma exceptionally rich in eosinophilic granular bodies (EGBs)
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M. 58 yr. Basilar artery thrombosis in sickle cell disease M. 62 yr.  Progressive multifocal leucoencephalopathy   (PML)
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14/8/12
M. 54 yr.  Cerebral histoplasmosis M. 44 yr. Oncocytoma (null cell adenoma) of  pituitary
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3/6/12
M. 68 yr.  Granular cell astrocytoma of brain. F. 20 yr. Epidural thoracic ganglioneuroblastoma
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26/3/12
F. 37 yr.  Intracranial solitary fibrous tumor developing multiple bone metastases 3 years after craniotomy Same case, vertebral metastasis at T11 with cord compression
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M. 21 yr.  Primary meningeal sarcoma with polyphenotypic antigen expression M. 51 yr. Secretory meningioma  at cerebello-pontine angle masquerading as  schwannoma on MRI
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M. 43 yr. Giant bilateral fronto-parietal 
meningioma  with hyperostosis and brain compression
M. 69 yr. Frontal meningioma  with hyperostosis and bone destruction. Pictured : ischemic necrosis of tumor and bone trabeculae
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17/2/12
F. 58 yr.  Giant cell glioblastoma with a component of conventional glioblastoma multiforme F. 45 yr. Left parietal ganglioglioma
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M. 12 yr. Small solid ganglioglioma of right insula F. 51 yr. Solid-cystic ganglioglioma of right temporal and occipital regions
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18/12/11
M. 24 yr.  Atypical central neurocytoma. 
Pictured : atypical mitosis
M. 35 yr. Classical central neurocytoma.
Pictured : dot positivity for chromogranin
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M. 28 yr. Subependymal giant cell astrocytoma (SEGA) unassociated with tuberous sclerosis.  Pictured : MAP2 positive neuron-like cell  M. 26 yr.  Central neurocytoma. 
Pictured : GFAP-positive cell processes among negative tumor cells 
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F. 44 yr.  Ectopic invasive pituitary adenoma centered in sphenoid sinus, spilling into left nasal cavity. Normal sella turcica. 
Pictured : growth hormone positive tumor cells 
F. 54 yr. Cerebro-spinal sarcoidosis. 
Pictured : non-caseating epithelioid  and giant cell granulomas 
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11/11/11
M. 16 yr. Left frontal cavernoma, two-year followup. Pictured : MRI one year after first bleeding;  surgical specimen under stereomicroscope showing thrombi F. 28 yr. Cavernoma of right cingulate gyrus. Surgical specimen under stereomicroscope (external surface)
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M. 48 yr.  Primary necrotizing vasculitis of central nervous system.  M. 28 yr. Papillary craniopharyngioma
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F. 46 yr. Bilateral frontal gliomatosis cerebri involving genu of corpus callosum F. 42 yr. Centroencephalic diffuse large B-cell lymphoma
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18/9/11
F. 52 yr.  Anaplastic parietal ganglioglioma M. 55 yr. Frontal ganglioglioma with pilocytic glial component
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M. 52 yr.  Sinonasal neuroendocrine carcinoma M. 63 yr. Langerhans cell histiocytosis of orbit
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22/8/11
M. 70 yr.  Atypical meningioma with intra and extracranial growth replacing left side of frontal bone F. 63 yr. Giant meningioma of olfactory groove. Histologically, fibroblastic pattern with nuclear palisading mimicking schwannoma
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F. 57 yr. Meningioma en plaque of middle fossa infiltrating cavernous sinus and middle ear M. 60 yr. Metastatic melanoma in genu of corpus callosum mimicking butterfly glioma 
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M. 49 yr. Cerebellar abscess by the fungus Paracoccidioides brasiliensis M. 71 yr. Cerebellar abscess caused by Paracoccidioides brasiliensis (another case seen  one week after the previous one, Velpeau's law)
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11/6/11
M. 63 yr. Paracoccidioidomycoma of cerebellopontine angle  (pseudotumoral granuloma caused by the fungus Paracoccidioides brasiliensis) M. 38 yr.  Mucormycosis of nasal cavity, orbit and brain
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M. 42 yr. Primary extracerebral meningeal glioma F. 44 yr.  Tanycytic ependymoma of  lumbar spinal cord
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15/4/11
F. 9 yr. Supratentorial primitive neuroectodermal tumor (PNET) F. 71 yr. Extradural spinal leiomyoma
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M. 55 yr. Temporal pilocytic astrocytoma F. 66 yr. Pilocytic astrocytoma of cerebellar vermis in the 7th decade
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Updated 5/1/2020 e-mails : gradanat@yahoo.com.br___gradanat@unicamp.br 
....
Additions  2003 - 2006
2007 - 2010
2011 - 2014 2015 -  2018 2019 to present
....
General and Special Pathology  Neuropathology and Neuroimaging Neuroimaging Basics Neuroimaging - Cases
Alphabetical index (Pathology) Alphabetical index (Neuro) Neuro Image Bank Neuropathology - Cases
English Homepage This page in Portuguese Histological techniques New additions
.....