Anatpat-UNICAMP

NEUROPATHOLOGY - NEUROIMAGING
CLICKABLE TEACHING SUMMARY - 1

GENERAL

VASCULAR

TRAUMA

INFLAMMATION

TUMORS

NEUROPATH HOMEPAGE

GENERAL NEUROPATHOLOGY

NORMAL NEURONS AND GLIA

Text: normal nervous tissue
(please note, all texts and final illustrated pages in Portuguese only)
Image bank: normal nervous tissue : neurons, astrocytes, microglia.

Electron microscopy of normal cerebral cortex.

Immunohistochemistry of normal glial cells.
Immunohistochemistry of normal glial cells.	astrocytes (GFAP)	microglia (CD68)

Microscopy:
(normal cerebral cortex and spinal cord).

GENERAL PATHOLOGY OF NEURONS AND GLIA

Text: pathological nervous tissue
Image bank: pathologic tissue: neurons, astrocytes, microglia

Example: ischemic lesion of cerebral cortex in a young man.
	normal neuron	necrotic neuron

Immunohistochemistry of pathological glial cells
Immunohistochemistry of pathological glial cells	astrocytes (GFAP)	microglia (CD68)

Microscopy:	Early cerebral infarct	Old cerebral infarct

INTRACRANIAL HYPERTENSION, BRAIN EDEMA, CEREBRAL HERNIATIONS

Text: Intracranial hypertension, brain edema, herniations
Specimens: brain edema, herniations

Image bank: brain edema, herniations

uncal herniation	Duret hemorrhage	tonsillar herniation	subfalcine herniation

Neuroimaging: Brain edema. Examples
Vascular pathology: ischemic infarcts 2, 4, 6; hemorrhage 2; aneurysm 5.
Trauma: skull fractures 4, pneumocephalus 3, contusions 3, acute subdural hematoma 2,
brain swelling 1, bullet wounds 2.
Inflammation: herpes encephalitis 1, purulent meningitis 1, brain abscess 1,
toxoplasmosis 6.
Tumors: diffuse astrocytoma 3, glioblastoma 2, 5; metastases 2, 16.

Vascular	Trauma	Inflammation	Tumors

Herniations. Examples
Uncal herniation in : hemorrhagic infarct 3; herpes encephalitis 2; diffuse astrocytoma 2.
Tonsillar herniation in: pilocytic astrocytoma 1; medulloblastoma 2; metastases 10, 15; schwannoma 1.
Subfalcine herniation in: brain abscess 1; toxoplasmosis 1; diffuse astrocytoma 2; glioblastoma 5, 6; metastases 2, 17.

uncal	tonsillar	subfalcine

HYDROCEPHALUS

Text
Specimens:

Image Bank		Neuroimaging

Hydrocephalus in neuroimaging: Examples
Vascular pathology: ischemic infarcts 13.
Trauma: acute subdural hematoma 3, diffuse axonal injury 3.
Inflammation: brain abscess 8, neurotuberculosis 6, toxoplasmosis 7, cysticercosis 7, 9, 13.
Tumors: glioblastoma 2; pilocytic astrocytoma 2, medulloblastoma 2, meningioma 5, schwannoma 1, metastases 1, 10.