Diagnosis: Renal
artery dissection. Extensive renal infarct. Thrombotic microangiopathy
consistent
with disseminated intravascular coagulation. Comments: Hypertension
is the major risk factor in arterial dissection. Less frequently,
dissections
are related to inherited or acquired connective tissue disorders
causing
abnormal vascular extracellular matrix, however, there are cases of
unknown
cause. In this particular case, a complication was an extensive renal
infarct.
The thrombotic microangiopathy represented by microthrombi in the
glomerular
capillaries most probably correspond to a disseminated intravascular
coagulation
(DIC) because no lesions were seen in the renal vessels. DIC seems to
be a
secondary phenomenon associated with the artery dissection (Yoon SH et
al. Disseminated
intravascular coagulation associated with aortic dissecting aneurysm.
Korean J
Intern Med 2004;19:134-136). |