Diagnosis: Granulation tissue and chronic active cystitis with scattered giant cells.     

            Comment: The atypical mesenchymal cells seen in this case may be seen in cystitis as well as in the normal lamina propria of the bladder. In the first description of these cells it was coined the term giant cell cystitis but it is our opinion that the finding does not constitute a distinctive entity. These cells are enlarged, hyperchromatic and show multiple nuclei. Similar cells may be seen in lamina propria after radiation or chemotherapy.